Self-sustained asynchronous irregular states and Up–Down states in thalamic, cortical and thalamocortical networks of nonlinear integrate-and-fire neurons

@article{Destexhe2009SelfsustainedAI,
  title={Self-sustained asynchronous irregular states and Up–Down states in thalamic, cortical and thalamocortical networks of nonlinear integrate-and-fire neurons},
  author={Alain Destexhe},
  journal={Journal of Computational Neuroscience},
  year={2009},
  volume={27},
  pages={493-506}
}
Randomly-connected networks of integrate-and-fire (IF) neurons are known to display asynchronous irregular (AI) activity states, which resemble the discharge activity recorded in the cerebral cortex of awake animals. However, it is not clear whether such activity states are specific to simple IF models, or if they also exist in networks where neurons are endowed with complex intrinsic properties similar to electrophysiological measurements. Here, we investigate the occurrence of AI states in… CONTINUE READING

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