Self-selection of the analgesic drug carprofen by lame broiler chickens

  title={Self-selection of the analgesic drug carprofen by lame broiler chickens},
  author={T. C. Danbury and Claire A. Weeks and Avril E. Waterman-Pearson and S. C. Kestin and J P Chambers},
  journal={Veterinary Record},
  pages={307 - 311}
Lame and sound broilers, selected from commercial flocks, were trained to discriminate between different coloured feeds, one of which contained carprofen. The two feeds were then offered simultaneously and the birds were allowed to select their own diet from the two feeds. In an initial study to assess the most appropriate concentration of drug, the plasma concentrations of carprofen were linearly related to the birds' dietary intake. The walking ability of lame birds was also significantly… 

Use of vitamin D to reduce lameness in broilers reared in harsh environments

Results suggest that dietary vitamin D is effective in decreasing the severity of lameness by reducing tibial dyschondroplasia and other leg abnormalities of a fast-growing broiler strain reared under harsh conditions.

Treatment of Joint Inflammatory Diseases in the Lame Backyard Chickens with NSAIDs

Results of the current study revealed that the meloxicam was the drug of choice with relative safety for treatment of joint inflammatory diseases in chickens.

The behaviour of broiler chickens and its modification by lameness.

Motor ability and self-selection of an analgesic drug by fast-growing chickens

There was an interaction of sex with left-right preference for feeder location, and the hypothesis that broilers with higher gait scores, if experiencing pain, would prefer diets with higher doses of carprofen was rejected.

Toxicological effects of diclofenac in four avian species

Investigation of toxico-pathological effects of diclofenac in different avian species found that Severity of clinical disease increased in a dose-related manner and was most severe in broiler chicks, followed by pigeons, Japanese quail, and was least severe in mynah.


Data showed that the concentration of 500 mg propolis/kg diet did not significantly influence the humoral immune response of broiler against NDV, and the highest haemagglutination inhibiting antibody titer was obtained from birds fed diets supplemented with 125 and 250 mg propoli/ kg diet at 35 days of age.

Study of potential toxic effects of acetylsalicylic acid upon short-term repeated oral administration in chickens

It was concluded that acetylsalicylic acid (10 mg/kg) upon repeated oral administration daily for a period of five days found toxic in chickens.

Effect of the analgesic butorphanol on activity behaviour in turkeys (Meleagris gallopavo).




Effect of carprofen on lameness in broiler chickens

Carprofen substantially increased the speed of lame birds, providing evidence that birds with moderate lameness suffer pain when they walk.

Comparison of the postoperative analgesic and sedative effects of carprofen and papaveretum in the dog

Carprofen provided profound analgesia which was as effective and of longer duration than that produced by papaveretum, and was associated with significantly less postoperative sedation and a quicker return to the normal conscious state.

Pharmacodynamic evaluation of the peripheral pain inhibition by carprofen and flunixin in the horse.

Carprofen, flunixin meglumine and placebo in the form of a physiological solution of sodium chloride were tested in an open randomised cross-over trial for analgesic efficacy in horses with two external skin-stimulation systems to find an optimal way to measure pain perception after stimulating the skin with high temperature.

Pharmacodynamics and enantioselective pharmacokinetics of carprofen in the cat.

Prevalence of leg weakness in broiler chickens and its relationship with genotype

The results indicated that genetic factors were an important cause of leg weakness in broilers and also identified a possible relationship between liveweight and leg weakness.

Skeletal disorders in the fowl: a review.

  • B. Thorp
  • Biology, Medicine
    Avian pathology : journal of the W.V.P.A
  • 1994
Bone conditions in poultry can be grouped under three headings based on the age and type of fowls affected, and are indicative of the genetic and production stresses applied to the skeleton.

Nonsteroidal anti-inflammatory drugs and corticosteroids for the management of canine osteoarthritis.