Self-report of cognitive impairment and mini-mental state examination performance in PRKN, LRRK2, and GBA carriers with early onset Parkinson's disease

@article{Alcalay2010SelfreportOC,
  title={Self-report of cognitive impairment and mini-mental state examination performance in PRKN, LRRK2, and GBA carriers with early onset Parkinson's disease},
  author={Roy N. Alcalay and Helen Mejia-Santana and Ming Xin Tang and Brian C. Rakitin and Llency Rosado and Barbara M. Ross and Miguel Verbitsky and Sergey Kisselev and Elan D. Louis and Cynthia L. Comella and Amy Colcher and Danna Jennings and Martha A. Nance and Susan B. Bressman and William K. Scott and Caroline M. Tanner and Susan F. Mickel and Howard F Andrews and Cheryl H. Waters and Stanley Fahn and Lucien J. C{\^o}t{\'e} and Steven Frucht and Blair Ford and Michael Rezak and Kevin Novak and Joseph H. Friedman and Ronald F. Pfeiffer and Laura K. Marsh and Bradley C. Hiner and Andrew D. Siderowf and Ruth Ottman and Lorraine N Clark and Karen S. Marder and Elise Caccappolo},
  journal={Journal of Clinical and Experimental Neuropsychology},
  year={2010},
  volume={32},
  pages={775 - 779}
}
  • Roy N. Alcalay, Helen Mejia-Santana, +31 authors Elise Caccappolo
  • Published 2010
  • Psychology, Medicine
  • Journal of Clinical and Experimental Neuropsychology
  • While little is known about risk factors for cognitive impairment in early onset Parkinson disease (EOPD), postmortem studies have shown an association between dementia with Lewy bodies (DLB) and glucocerebrosidase (GBA) mutation. We compared Mini-Mental State Examination (MMSE) performance and self-reported cognitive impairment in 699 EOPD participants genotyped for mutations in parkin (PRKN), leucine-rich repeat kinase-2 (LRRK2), and GBA. Logistic regression was used to assess the association… CONTINUE READING

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 45 CITATIONS, ESTIMATED 36% COVERAGE

    Cognitive profile of LRRK2-related Parkinson's disease.

    Cognitive decline in Parkinson disease

    FILTER CITATIONS BY YEAR

    2011
    2019

    CITATION STATISTICS

    • 4 Highly Influenced Citations

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 23 REFERENCES

    Diagnostic procedures for Parkinson's disease dementia: recommendations from the movement disorder society task force.

    • B. Dubois, D. Burn, +18 authors M. Emre
    • Medicine, Psychology
    • Movement disorders : official journal of the Movement Disorder Society
    • 2007
    VIEW 1 EXCERPT

    Young-onset Parkinson's disease revisited--clinical features, natural history, and mortality.

    VIEW 1 EXCERPT

    Genotypic and phenotypic characteristics of Dutch patients with early onset Parkinson's disease.

    VIEW 1 EXCERPT

    Construction and validation of a Parkinson's disease mutation genotyping array for the Parkin gene.