Self-report of cognitive impairment and mini-mental state examination performance in PRKN, LRRK2, and GBA carriers with early onset Parkinson's disease.

@article{Alcalay2010SelfreportOC,
  title={Self-report of cognitive impairment and mini-mental state examination performance in PRKN, LRRK2, and GBA carriers with early onset Parkinson's disease.},
  author={Roy N Alcalay and Helen Mejia-Santana and Ming Xin Tang and Brian C. Rakitin and Llency Rosado and B. M. Ross and Miguel Verbitsky and Sergey Kisselev and Elan Daniel Louis and Cynthia L. Comella and Amy Colcher and Danna Jennings and Martha A. Nance and Susan Bressman and William K. Scott and Caroline M. Tanner and Susan F Mickel and Howard F. Andrews and Cheryl H. Waters and Stanley Fahn and Lucien J. Cot{\'e} and Steven J. Frucht and Blair Ford and Michael Rezak and Kevin E Novak and Joseph H Friedman and Ronald F. Pfeiffer and Laura Marsh and Bradley C. Hiner and Andrew D. Siderowf and Ruth Ottman and Lorraine N. Clark and Karen S. Marder and Elise Caccappolo},
  journal={Journal of clinical and experimental neuropsychology},
  year={2010},
  volume={32 7},
  pages={775-9}
}
While little is known about risk factors for cognitive impairment in early onset Parkinson disease (EOPD), postmortem studies have shown an association between dementia with Lewy bodies (DLB) and glucocerebrosidase (GBA) mutation. We compared Mini-Mental State Examination (MMSE) performance and self-reported cognitive impairment in 699 EOPD participants genotyped for mutations in parkin (PRKN), leucine-rich repeat kinase-2 (LRRK2), and GBA. Logistic regression was used to assess the association… CONTINUE READING

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Self - report of cognitive impairment and mini - mental state examination performance in PRKN , LRRK2 , and GBA carriers with early onset Parkinson 's disease .
We compared Mini - Mental State Examination ( MMSE ) performance and self - reported cognitive impairment in 699 EOPD participants genotyped for mutations in parkin ( PRKN ) , leucine - rich repeat kinase-2 ( LRRK2 ) , and GBA .
We compared Mini - Mental State Examination ( MMSE ) performance and self - reported cognitive impairment in 699 EOPD participants genotyped for mutations in parkin ( PRKN ) , leucine - rich repeat kinase-2 ( LRRK2 ) , and GBA .
Self - report of cognitive impairment and mini - mental state examination performance in PRKN , LRRK2 , and GBA carriers with early onset Parkinson 's disease .
We compared Mini - Mental State Examination ( MMSE ) performance and self - reported cognitive impairment in 699 EOPD participants genotyped for mutations in parkin ( PRKN ) , leucine - rich repeat kinase-2 ( LRRK2 ) , and GBA .
Self - report of cognitive impairment and mini - mental state examination performance in PRKN , LRRK2 , and GBA carriers with early onset Parkinson 's disease .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
Self - report of cognitive impairment and mini - mental state examination performance in PRKN , LRRK2 , and GBA carriers with early onset Parkinson 's disease .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
While little is known about risk factors for cognitive impairment in early onset Parkinson disease ( EOPD ) , postmortem studies have shown an association between dementia with Lewy bodies ( DLB ) and glucocerebrosidase ( GBA ) mutation .
PARK2 geneGene associated with diseaseParkinson Disease
Self - report of cognitive impairment and mini - mental state examination performance in PRKN , LRRK2 , and GBA carriers with early onset Parkinson 's disease .
LRRK2 geneGene associated with diseaseParkinson Disease
Self - report of cognitive impairment and mini - mental state examination performance in PRKN , LRRK2 , and GBA carriers with early onset Parkinson 's disease .
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