Self-replication with errors. A model for polynucleotide replication.


A model for polynucleotide replication is presented and analyzed by means of perturbation theory. Two basic assumptions allow handling of sequences up to a chain length of v approximately 80 explicitly: point mutations are restricted to a two-digit model and individual sequences are subsumed into mutant classes. Perturbation theory is in excellent agreement with the exact results for long enough sequences (v greater than 20).

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@article{Swetina1982SelfreplicationWE, title={Self-replication with errors. A model for polynucleotide replication.}, author={Joerg Swetina and Peter Schuster}, journal={Biophysical chemistry}, year={1982}, volume={16 4}, pages={329-45} }