Self-repair promotes microtubule rescue

  title={Self-repair promotes microtubule rescue},
  author={Charlotte Aumeier and Laura Schaedel and J{\'e}r{\'e}mie Gaillard and K. P. Ludwig John and Laurent Blanchoin and Manuel Th{\'e}ry},
  booktitle={Nature Cell Biology},
The dynamic instability of microtubules is characterized by slow growth phases stochastically interrupted by rapid depolymerizations called catastrophes. Rescue events can arrest the depolymerization and restore microtubule elongation. However, the origin of these rescue events remains unexplained. Here we show that microtubule lattice self-repair, in structurally damaged sites, is responsible for the rescue of microtubule growth. Tubulin photo-conversion in cells revealed that free tubulin… CONTINUE READING
This paper has been referenced on Twitter 73 times. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.

Explore Further: Topics Discussed in This Paper


Publications citing this paper.
Showing 1-10 of 12 citations


Publications referenced by this paper.
Showing 1-10 of 49 references