Self-renewal of the gastric epithelium from stem and progenitor cells.

  title={Self-renewal of the gastric epithelium from stem and progenitor cells.},
  author={Werner Hoffmann},
  journal={Frontiers in bioscience},
The mammalian gastric mucosa and its glands are both of endodermal origin and together represent a tight barrier to the outside world. Here, two types of gastric units form homeostatic systems, i.e. fundic and antral units, showing continual bi-directional self-renewal via differentiation from stem and progenitor cells. This review describes recent developments concerning the different populations of gastric stem cells as well as the various gastric epithelial cell types and their self-renewal… CONTINUE READING

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