Self-renewal of murine embryonic stem cells is supported by the serine/threonine kinases Pim-1 and Pim-3.

@article{Aksoy2007SelfrenewalOM,
  title={Self-renewal of murine embryonic stem cells is supported by the serine/threonine kinases Pim-1 and Pim-3.},
  author={Ir{\`e}ne Aksoy and Caline Sakabedoyan and Pierre-Yves Bourillot and Anna Malashicheva and Jimmy Mancip and Kenneth Knoblauch and Marielle Afanassieff and Pierre Savatier},
  journal={Stem cells},
  year={2007},
  volume={25 12},
  pages={2996-3004}
}
pim-1 and pim-3 encode serine/threonine kinases involved in the regulation of cell proliferation and apoptosis in response to cytokine stimulation. We analyzed the regulation of pim-1 and pim-3 by the leukemia inhibitory factor (LIF)/gp130/signal transducer and activator of transcription-3 (STAT3) pathway and the role of Pim-1 and Pim-3 kinases in mouse… CONTINUE READING

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