Self-renewal of human embryonic stem cells on defined synthetic electrospun nanofibers.

Abstract

Human embryonic stem cells (hESCs) are conventionally expanded and maintained in vitro on biological substrates. Synthetic electrospun polymer nanofibers have the potential to act as non-biological substrates in the culture of hESCs. Three synthetic, FDA approved polymers: poly-ɛ-caprolactone (PCL), poly-L-lactic acid (PLLA) and poly lactic-co-glycolic acid… (More)
DOI: 10.1088/1748-6041/10/6/065017

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