Self-renewal made simple.


Embryonic stem cells (ESCs) are prone to differentiation in culture, suggesting that maintenance of the pluripotent state must be actively induced. In a recent issue of Nature, Ying et al. (2008) use soluble small molecules to inhibit pro-differentiation signals and reveal ESC self-renewal as a default cell fate. 
DOI: 10.1016/j.stem.2008.06.007


Cite this paper

@article{Dunn2008SelfrenewalMS, title={Self-renewal made simple.}, author={N. Ray Dunn}, journal={Cell stem cell}, year={2008}, volume={3 1}, pages={7-8} }