Self-recognition by an intrinsically disordered protein.

Abstract

The intrinsically disordered translocation domain (T-domain) of the protein antibiotic colicin N binds to periplasmic receptors of target Escherichia coli cells in order to penetrate their inner membranes. We report here that the specific 27 consecutive residues of the T-domain of colicin N known to bind to the helper protein TolA in target cells also… (More)
DOI: 10.1016/j.febslet.2008.06.022

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