Self-organizing optic-cup morphogenesis in three-dimensional culture.


Balanced organogenesis requires the orchestration of multiple cellular interactions to create the collective cell behaviours that progressively shape developing tissues. It is currently unclear how individual, localized parts are able to coordinate with each other to develop a whole organ shape. Here we report the dynamic, autonomous formation of the optic… (More)
DOI: 10.1038/nature09941


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