Self-organization process in newborn skin organoid formation inspires strategy to restore hair regeneration of adult cells.

@article{Lei2017SelforganizationPI,
  title={Self-organization process in newborn skin organoid formation inspires strategy to restore hair regeneration of adult cells.},
  author={Mingxing Lei and Linus J. Schumacher and Yung-Chih Lai and Wen-Tau Juan and Chao-Yuan Yeh and P Wu and T X Jiang and Ruth E. Baker and Randall B Widelitz and Li Yang and Cheng-ming Chuong},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2017},
  volume={114 34},
  pages={
          E7101-E7110
        }
}
Organoids made from dissociated progenitor cells undergo tissue-like organization. This in vitro self-organization process is not identical to embryonic organ formation, but it achieves a similar phenotype in vivo. This implies genetic codes do not specify morphology directly; instead, complex tissue architectures may be achieved through several… CONTINUE READING