Self-organization of keratin intermediate filaments into cross-linked networks

Abstract

Keratins, the largest subgroup of intermediate filament (IF) proteins, form a network of 10-nm filaments built from type I/II heterodimers in epithelial cells. A major function of keratin IFs is to protect epithelial cells from mechanical stress. Like filamentous actin, keratin IFs must be cross-linked in vitro to achieve the high level of mechanical… (More)
DOI: 10.1083/jcb.200810196

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Cite this paper

@inproceedings{Lee2009SelforganizationOK, title={Self-organization of keratin intermediate filaments into cross-linked networks}, author={Chang-Hun Lee and Pierre A. Coulombe}, booktitle={The Journal of cell biology}, year={2009} }