Self-nanoemulsifying granules of ezetimibe: design, optimization and evaluation.

@article{Dixit2008SelfnanoemulsifyingGO,
  title={Self-nanoemulsifying granules of ezetimibe: design, optimization and evaluation.},
  author={Rahul P Dixit and Mangal Shailesh Nagarsenker},
  journal={European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences},
  year={2008},
  volume={35 3},
  pages={183-92}
}
Self-nanoemulsifying granules (SNGs) were formulated with the objective of enhancing the bioavailability of the ezetimibe. Various modified oils, surfactant and cosurfactant mixtures were used and composition of self-nanoemulsifying system (SNS) was optimized. SNS diluted and resultant emulsion was characterized for mean globule size and stability. The self-nanoemulsifying systems were formulated into free flowing self-nanoemulsifying granules using varying proportions of hydrophilic colloidal… CONTINUE READING

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