Self-destructiveness and serotonin function in bulimia nervosa.

  title={Self-destructiveness and serotonin function in bulimia nervosa.},
  author={Howard Steiger and Naomi M Koerner and Marla J Engelberg and Mimi Isr{\"a}el and Ng Mien Kwong Ng Ying Kin and Simon N. Young},
  journal={Psychiatry research},
  volume={103 1},
Studies have linked bulimia nervosa (BN) to alterations in brain serotonin (5-hydroxytryptamine: 5-HT) activity and to heightened propensity for parasuicidality and self-injuriousness. The coincidence of self-destructiveness and 5-HT abnormality in BN is of interest, given documentation (in various populations) of an inverse association between 5-HT activity and potential for self-harm. The present study examined the connection between 5-HT status and self-destructiveness in BN. Structured… CONTINUE READING