Self-crosslinked oxidized alginate/gelatin hydrogel as injectable, adhesive biomimetic scaffolds for cartilage regeneration.

@article{Balakrishnan2014SelfcrosslinkedOA,
  title={Self-crosslinked oxidized alginate/gelatin hydrogel as injectable, adhesive biomimetic scaffolds for cartilage regeneration.},
  author={Biji Balakrishnan and Nitin S Joshi and Athipettah Jayakrishnan and Rinti Banerjee},
  journal={Acta biomaterialia},
  year={2014},
  volume={10 8},
  pages={3650-63}
}
Biopolymeric hydrogels that mimic the properties of extracellular matrix have great potential in promoting cellular migration and proliferation for tissue regeneration. The authors reported earlier that rapidly gelling, biodegradable, injectable hydrogels can be prepared by self-crosslinking of periodate oxidized alginate and gelatin in the presence of borax, without using any toxic crosslinking agents. The present paper investigates the suitability of this hydrogel as a minimally invasive… CONTINUE READING
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