Self-cleaving ribozymes of hepatitis delta virus RNA.

  title={Self-cleaving ribozymes of hepatitis delta virus RNA.},
  author={Michael D. Been and Gene S. Wickham},
  journal={European journal of biochemistry},
  volume={247 3},
Hepatitis delta virus (HDV) is a small single-stranded RNA satellite of hepatitis B virus. Although it is a human pathogen, it shares a number of features with a subset of the small plant satellite RNA viruses, including self-cleaving sequences in the genomic and antigenomic sequences of the viral RNA. The self-cleaving sequence is critical to viral replication and is thought to function as a ribozyme in vivo to process the products of rolling-circle replication to unit-length molecules. A… CONTINUE READING


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