Self-assembly of novel thiophene-based BODIPY Ru(II) rectangles: Potential antiproliferative agents selective against cancer cells.

Abstract

Novel Ru (2+2) rectangles were designed and synthesized by self-assembly of a new thiophene-functionalized dipyridyl BODIPY ligand, BDPS, and ruthenium (II) precursors. The complexes exhibited dose-dependent antiproliferative activities against cancer cells, where some compounds selectively kill cancer cells. The net fluorescence due to BODIPY allowed us to visualize their location inside cancer cells. Moreover, the metalla-rectangles displayed substantial propensity to bind with biomolecules.

DOI: 10.1002/chem.201704368

Cite this paper

@article{Gupta2017SelfassemblyON, title={Self-assembly of novel thiophene-based BODIPY Ru(II) rectangles: Potential antiproliferative agents selective against cancer cells.}, author={Gajendra Gupta and Abhishek Das and Sourav Panja and Ji Yeon Ryu and Junseong Lee and Nripendranath Mandal and Chang Yeon Lee}, journal={Chemistry}, year={2017} }