Self-assembling properties of porphyrinic photosensitizers and their effect on membrane interactions probed by NMR spectroscopy.

Aggregation and membrane penetration of porphyrinic photosensitizers play crucial roles for their efficacy in photodynamic therapy. The current study was aimed at comparing the aggregation behavior of selected photosensitizers and correlating it with membrane affinity. Self-assembling properties of 15 amphiphilic free-base chlorin and porphyrin derivatives… CONTINUE READING