Self-assembled proteinticle nanostructures for 3-dimensional display of antibodies.

Abstract

"Proteinticle" is a nano-scale protein particle that is self-assembled inside cells with constant 3D structure and surface topology. The binding of IgG to the B domain of Staphylococcal protein A (SPA(B)) molecules that are genetically inserted on the surface of proteinticle enables the variable domains of bound IgG to be well oriented to effectively… (More)
DOI: 10.1039/c4nr03635b

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