Self-assembled polymeric nanoparticles based on oleic acid-grafted chitosan oligosaccharide: biocompatibility, protein adsorption and cellular uptake.

@article{Zhang2012SelfassembledPN,
  title={Self-assembled polymeric nanoparticles based on oleic acid-grafted chitosan oligosaccharide: biocompatibility, protein adsorption and cellular uptake.},
  author={Jing Zhang and Xi Chen and Lu Huang and Jing Han and Xiao Fan Zhang},
  journal={Journal of materials science. Materials in medicine},
  year={2012},
  volume={23 7},
  pages={1775-83}
}
Oleic acid-grafted chitosan oligosaccharide (OA-g-CSO) was synthesized to prepare self-assembled nanoparticles by sonication at physiological pH value (7.4). The nanoparticles appeared to be spherical in shape with a diameter of 158.1 ± 64.3 nm. The biocompatibility of OA-g-CSO nanoparticles was evaluated in vitro via MTT assay and hemolysis test. The nanoparticles showed no cytotoxicity to mouse embryo fibroblasts and the hemolysis rates came well within permissible limits (<2 %) in the tested… CONTINUE READING

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Salicylic acid-grafted chitosan oligosaccharide nanoparticle for paclitaxel delivery

  • XH Wei, YP Niu, YY Xu, YZ Du, FQ Hu, H. Yuan
  • J Bioact Compat Polym
  • 2010
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