Self-assembled or mixed peptide amphiphile micelles from Herpes simplex virus glycoproteins as potential immunomodulatory treatment

@inproceedings{Accardo2014SelfassembledOM,
  title={Self-assembled or mixed peptide amphiphile micelles from Herpes simplex virus glycoproteins as potential immunomodulatory treatment},
  author={Antonella Accardo and Mariateresa Vitiello and Diego Tesauro and Marilena Galdiero and Emiliana Finamore and Francesca Martora and Rosalba Mansi and Paola Ringhieri and Giancarlo Morelli},
  booktitle={International journal of nanomedicine},
  year={2014}
}
The use of micelle aggregates formed from peptide amphiphiles (PAs) as potential synthetic self-adjuvant vaccines to treat Herpes simplex virus (HSV) infection are reported here. The PAs were based on epitopes gB409-505 and gD301-309, selected from HSV envelope glycoprotein B (gB) and glycoprotein D (gD), that had their N-terminus modified with hydrophobic moieties containing two C18 hydrocarbon chains. Pure and mixed micelles of gB and/or gD peptide epitopes were easily prepared after starting… CONTINUE READING

Citations

Publications citing this paper.

References

Publications referenced by this paper.
Showing 1-10 of 43 references

Peptide-based targeting strategies for simultaneous imaging and therapy with nanovectors

  • A Accardo, D Tesauro, G. Morelli
  • Polym J
  • 2013

Similar Papers

Loading similar papers…