Self-assembled biodegradable amphiphilic PEG-PCL-lPEI triblock copolymers at the borderline between micelles and nanoparticles designed for drug and gene delivery.

Abstract

Amphiphilic PEG-PCL-PEI triblock copolymers self-assemble into nano-scaled, positively charged, multifunctional carriers, suitable for drug and gene delivery. A set of block copolymers with varying hydrophilic/hydrophobic ratio (systematically altered at the borderline of micelle and particle forming polymers) was synthesized, characterized and assembled… (More)
DOI: 10.1016/j.biomaterials.2011.06.064

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Cite this paper

@article{Endres2011SelfassembledBA, title={Self-assembled biodegradable amphiphilic PEG-PCL-lPEI triblock copolymers at the borderline between micelles and nanoparticles designed for drug and gene delivery.}, author={Thomas K Endres and Moritz Beck-Broichsitter and O. E. Samsonova and Thomas Renette and Thomas H. Kissel}, journal={Biomaterials}, year={2011}, volume={32 30}, pages={7721-31} }