Self-assembled aptamer-based drug carriers for bispecific cytotoxicity to cancer cells.


Monovalent aptamers can deliver drugs to target cells by specific recognition. However, different cancer subtypes are distinguished by heterogeneous biomarkers and one single aptamer is unable to recognize all clinical samples from different patients with even the same type of cancers. To address heterogeneity among cancer subtypes for targeted drug… (More)
DOI: 10.1002/asia.201101060