Self-administration of delta 9-tetrahydrocannabinol by rats.

  title={Self-administration of delta 9-tetrahydrocannabinol by rats.},
  author={Reinaldo Naoto Takahashi and George Singer},
  journal={Pharmacology, biochemistry, and behavior},
  volume={11 6},
The present study examines the dose-response pattern of delta 9-tetrahydrocannabinol self-injection in naive rats at 80% reduced body weight and 100% body weight, both conditions with a fixed-time 1 min (FT-1) food delivery schedule. The results indicated that food deprived animals tested on a FT-1 min schedule self-injected low doses of delta 9-THC at a higher rate than those animals at 100% body weight and on a FT-1 min schedule. Animals at 80% reduced body weight without a schedule did not… CONTINUE READING