Self-Tuning Spectral Clustering for Full-length Viral Quasispecies Reconstruction with PacBio Long Reads

@inproceedings{Jiao2017SelfTuningSC,
  title={Self-Tuning Spectral Clustering for Full-length Viral Quasispecies Reconstruction with PacBio Long Reads},
  author={Xiaoli Jiao and Hiromi Imamichi and Tauseef Rehman and Rishub Nahar and Robin L. Dewar and H. Clifford Lane and Tomozumi Imamichi and Brad T. Sherman},
  booktitle={BCB},
  year={2017}
}
Many of the infectious diseases which have jeopardized and still are a threat to public health are caused by RNA viruses, including HIV, HCV, Influenza virus, Ebola virus and Zika virus. Because of a high rate of mutations and recombination events, rapidly evolving RNA viruses prevail within a host as a collection of closely related variants, referred to as viral quasi-species. Uncovering the genetic diversity (i.e., inferring viral haplotypes and their proportions in the population) of an RNA… CONTINUE READING
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