Self-Regulation of Candida albicans Population Size during GI Colonization

  title={Self-Regulation of Candida albicans Population Size during GI Colonization},
  author={Sarah E White and Ari S Rosenbach and Paul Lephart and Diem H.D. Nguyen and Alana Benjamin and Saul Tzipori and Malcolm Whiteway and Joan C Mecsas and Carol A. Kumamoto},
  journal={PLoS Pathogens},
  pages={957 - 962}
Interactions between colonizing commensal microorganisms and their hosts play important roles in health and disease. The opportunistic fungal pathogen Candida albicans is a common component of human intestinal flora. To gain insight into C. albicans colonization, genes expressed by fungi grown within a host were studied. The EFH1 gene, encoding a putative transcription factor, was highly expressed during growth of C. albicans in the intestinal tract. Counterintuitively, an efh1 null mutant… CONTINUE READING


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