Self-Referential Processing, Rumination, and Cortical Midline Structures in Major Depression

  title={Self-Referential Processing, Rumination, and Cortical Midline Structures in Major Depression},
  author={Ayna Baladi Nejad and Philippe Fossati and C{\'e}dric Lemogne},
  booktitle={Front. Hum. Neurosci.},
Major depression is associated with a bias toward negative emotional processing and increased self-focus, i.e., the process by which one engages in self-referential processing. The increased self-focus in depression is suggested to be of a persistent, repetitive and self-critical nature, and is conceptualized as ruminative brooding. The role of the medial prefrontal cortex in self-referential processing has been previously emphasized in acute major depression. There is increasing evidence that… CONTINUE READING
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