Self Containment, a Property of Modular RNA Structures, Distinguishes microRNAs

@article{Lee2008SelfCA,
  title={Self Containment, a Property of Modular RNA Structures, Distinguishes microRNAs},
  author={Miler T. Lee and Junhyong Kim},
  journal={PLoS Computational Biology},
  year={2008},
  volume={4},
  pages={843 - 854}
}
RNA molecules will tend to adopt a folded conformation through the pairing of bases on a single strand; the resulting so-called secondary structure is critical to the function of many types of RNA. The secondary structure of a particular substring of functional RNA may depend on its surrounding sequence. Yet, some RNAs such as microRNAs retain their specific structures during biogenesis, which involves extraction of the substructure from a larger structural context, while other functional RNAs… CONTINUE READING
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