Self-Assembly of Antimicrobial Peptides on Gold Nanodots: Against Multidrug-Resistant Bacteria and Wound-Healing Application

@inproceedings{Chen2015SelfAssemblyOA,
  title={Self-Assembly of Antimicrobial Peptides on Gold Nanodots: Against Multidrug-Resistant Bacteria and Wound-Healing Application},
  author={Weinong Chen and Huan-Tsung Chang and Jenn-Kan Lu and Yi-Cheng Huang and Scott G Harroun and Yu-ting Tseng and Yu-Jia Li and Chih-Ching Huang},
  year={2015}
}
Photoluminescent gold nanodots (Au NDs) are prepared via etching and codeposition of hybridized ligands, an antimicrobial peptide (surfactin; SFT), and 1-dodecanethiol (DT), on gold nanoparticles (≈3.2 nm). As-prepared ultrasmall SFT/DT–Au NDs (size ≈2.5 nm) are a highly efficient antimicrobial agent. The photoluminescence properties and stability as well as the antimicrobial activity of SFT/DT–Au NDs are highly dependent on the density of SFT on Au NDs. Relative to SFT, SFT/DT–Au NDs exhibit… CONTINUE READING

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