Self-Assembling Peptide Nanofiber Scaffolds Accelerate Wound Healing

@article{Schneider2008SelfAssemblingPN,
  title={Self-Assembling Peptide Nanofiber Scaffolds Accelerate Wound Healing},
  author={Aurore Schneider and Jonathan A. Garlick and Christophe Egles},
  journal={PLoS ONE},
  year={2008},
  volume={3},
  pages={738 - 746}
}
Cutaneous wound repair regenerates skin integrity, but a chronic failure to heal results in compromised tissue function and increased morbidity. To address this, we have used an integrated approach, using nanobiotechnology to augment the rate of wound reepithelialization by combining self-assembling peptide (SAP) nanofiber scaffold and Epidermal Growth Factor (EGF). This SAP bioscaffold was tested in a bioengineered Human Skin Equivalent (HSE) tissue model that enabled wound reepithelialization… CONTINUE READING

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The Epidermis in Wound Healing

  • DT Rovee, HI Maibach
  • Boca Raton, FL: CRC Press LLC
  • 2003
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