Selenoprotein gene variants, toenail selenium levels, and risk for advanced prostate cancer.

@article{Geybels2014SelenoproteinGV,
  title={Selenoprotein gene variants, toenail selenium levels, and risk for advanced prostate cancer.},
  author={Milan S. Geybels and Piet A van den Brandt and Leo J Schouten and Frederik-Jan van Schooten and Simone G J van Breda and Margaret P. Rayman and Fiona R. Green and Bas A. J. Verhage},
  journal={Journal of the National Cancer Institute},
  year={2014},
  volume={106 3},
  pages={dju003}
}
Lower selenium levels have been associated with increased risk of prostate cancer (PCa), and genetic variation in the selenoprotein genes selenoprotein P (SEPP1) and glutathione peroxidase 1 (GPX1) is thought to modify this relationship. We investigated whether the association between toenail selenium levels and advanced PCa risk in the prospective Netherlands Cohort Study is modified by common genetic variation in SEPP1 and GPX1. Toenail clippings were used to determine selenium levels and to… CONTINUE READING

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  • 2013

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