Selenoprotein H is a nucleolar thioredoxin-like protein with a unique expression pattern.

@article{Novoselov2007SelenoproteinHI,
  title={Selenoprotein H is a nucleolar thioredoxin-like protein with a unique expression pattern.},
  author={Sergey V. Novoselov and Gregory V. Kryukov and X Xu and Bradley A. Carlson and Dolph Lee Hatfield and Vadim N. Gladyshev},
  journal={The Journal of biological chemistry},
  year={2007},
  volume={282 16},
  pages={11960-8}
}
The human selenoproteome consists of 25 known selenoproteins, but functions of many of these proteins are not known. Selenoprotein H (SelH) is a recently discovered 14-kDa mammalian protein with no sequence homology to functionally characterized proteins. By sensitive sequence and structure analyses, we identified SelH as a thioredoxin fold-like protein in which a conserved CXXU motif (cysteine separated by two other residues from selenocysteine) corresponds to the CXXC motif in thioredoxins… CONTINUE READING

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