Selenocompounds in Plants and Animals and their Biological Significance

@article{Whanger2002SelenocompoundsIP,
  title={Selenocompounds in Plants and Animals and their Biological Significance},
  author={Philip D. Whanger},
  journal={Journal of the American College of Nutrition},
  year={2002},
  volume={21},
  pages={223 - 232},
  url={https://api.semanticscholar.org/CorpusID:20483595}
}
There are several selenocompounds in tissues of plants and animals, and selenocysteine, the predominant selenoamino acid in tissues when inorganic selenium is given to animals, is one of them.
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486 Citations
Highly Influential Citations
15
Background Citations
165
Methods Citations
3
Results Citations
3

486 Citations

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Phytovolatilization of methylated Se compounds, offers an opportunity for the phytoextraction strategies to mitigate selenium laden soils.

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The identified metabolites enabled us to propose a metabolic pathway for the organic Se metabolites except TMSe in the plant roots: a monomethylseleno moiety commonly existing in SeMet, MeSeCys, and SeSug was cleaved off and conjugated with GSH, and then the CH3Se group was transferred to O-acetylserine to form MeSe Cys.

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The relative proportion of seleno-amino acids to SeO42− may be the key factor for the regulation of Cd accumulation in pak choi via treatment with selenite and selenate at the different growing stages.

Selenium species in the roots and shoots of chickpea plants treated with different concentrations of sodium selenite

The investigation of the Se species present in chickpea plants exposed to 0, 10, 25, 50, and 100 μM selenite in short- and long-term treatment studies showed that chick pea can accumulate Se in favorable concentrations and its transformation to bioavailable Se species may have positive impacts on human health and aid to implement Se into the diet.

Selenium speciation in enriched vegetables

Metabolomics of Selenium: Se Metabolites Based on Speciation Studies

The metabolism of selenium in the body was reviewed from the viewpoint of metabolomics based on speciation studies and recent results contradicted this.
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86 References

Selenoamino acids in tissues of rats administered inorganic selenium.

Investigations on selenium in wheat

Metabolism of Hydrogen Selenide and Methylated Selenides

Inorganic forms of selenium are readily metabolized to a variety of or-ganoselenium compounds in microorganisms, plants, and animals and can be detoxified by the formation of methylated selenides that are readily excreted and usually less toxic.

Distribution of free seleno-amino acids in plant tissue of Melilotus indica L. grown in selenium-laden soils.

Investigation of the distribution of seleno-amino acids in a Se-tolerant grassland legume species grown in Se-laden soils indicated that there was a five-fold increase in tissue selenocysteine concentration when the total tissue Se increased, but there was no further increase when the tissue total Se concentration increased.

Exclusion of selenium from proteins of selenium-tolerant astragalus species.

It is established that the ability to tolerate and to circumvent the toxic effects of selenium, characteristic of the accumulator species of Astragalus, is associated with a reduced incorporation of this element into protein.

Selenomethionine: a review of its nutritional significance, metabolism and toxicity.

It is shown that at constant intakes in the nutritional range, tissue Se levels increase until a steady state is established, preventing the build-up to toxic levels, and for animals, DL-Se-met is acceptable.

Characterization of tissue selenium profiles and anticarcinogenic responses in rats fed natural sources of selenium-rich products.

The experiments suggested that the high-selenium garlic and onion might have some unique attributes, and their ingestion did not lead to an exaggerated accumulation of tissue selenium, a concern that was shared by both selenomethionine and Brazil nut.

The incorporation of 75-Se-selenite into dystrophogenic pasture grass. The chemical nature of the seleno compounds formed and their availability to young ovine.

Data obtained from feeding various leaf preparations to lambs indicated that the water-soluble selenium compounds and the seleno-amino acids contained in the ethanol and proteolytic enzyme extracts were effectively absorbed and retained.

Selenium (Se) from high‐selenium broccoli is utilized differently than selenite, selenate and selenomethionine, but is more effective in inhibiting colon carcinogenesis

The reduction in incidence of chemically‐induced colon cancer by foods high in selenium (Se) was investigated in Fisher‐344 rats, demonstrating that foods with high Se bioavailability are not necessarily the most efficacious for cancer incidence reduction.

Deposition of dietary organic and inorganic selenium in rat erythrocyte proteins.

The dietary forms of Se influence the relative distribution of Se between GPx and Hb in erythrocytes, and this may be a factor contributing to the difference between human and animal ery Throatcytes.
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