Seleno-enzymes and seleno-compounds: the two faces of selenium

  title={Seleno-enzymes and seleno-compounds: the two faces of selenium},
  author={Xavier Forceville},
  journal={Critical Care},
  pages={180 - 180}
Selenium protects cells and inhibits many inflammatory cell mechanisms through antioxidant seleno-enzymes. Immunity improvement is illustrated by the study of Berger and colleagues, with reduction of nosocomial pneumonia in burnt patients under multi-trace-element supplementation. As seleno-compounds (especially sodium selenite) are pro-oxidant, however, administration above 800 microg/day may be dangerous in septic shock. Paradoxically, direct reversible pro-oxidative effects of seleno… CONTINUE READING

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