Selenium status is associated with colorectal cancer risk in the European prospective investigation of cancer and nutrition cohort.

@article{Hughes2015SeleniumSI,
  title={Selenium status is associated with colorectal cancer risk in the European prospective investigation of cancer and nutrition cohort.},
  author={David J Hughes and Veronika Fedirko and Mazda Jenab and Lutz Schomburg and Catherine M{\'e}plan and Heinz Freisling and H. B. Bueno-de-Mesquita and Sandra Hybsier and Natalia Becker and Magdalena Czuban and Anne Tj{\o}nneland and Malene Outzen and Marie-Christine Boutron-Ruault and Antoine Racine and Nadia Bastide and Tilman K{\"u}hn and Rudolf Kaaks and Dimitirios Trichopoulos and Antonia Trichopoulou and Martinus L{\o}vik and Salvatore Panico and P. H. Peeters and Elisabete Weiderpass and Guri Skeie and Engeset Dagrun and M. -D. Chirlaque and M Hernando S{\'a}nchez and Eva Ardanaz and Ingrid Ljuslinder and Maria Wennberg and Kathryn E Bradbury and Paolo Vineis and Alessio Naccarati and Domenico Palli and Heiner Boeing and Kim Overvad and M. Cano Dorronsoro and Paula Jakszyn and Amanda J. Cross and Jos{\'e} Ram{\'o}n Quir{\'o}s and Magdalena Stępień and So Yeon Kong and Mees Mosseveld and Elio Riboli and John Edward Hesketh},
  journal={International journal of cancer},
  year={2015},
  volume={136 5},
  pages={
          1149-61
        }
}
Suboptimal intakes of the micronutrient selenium (Se) are found in many parts of Europe. Low Se status may contribute to colorectal cancer (CRC) development. We assessed Se status by measuring serum levels of Se and Selenoprotein P (SePP) and examined the association with CRC risk in a nested case-control design (966 CRC cases; 966 matched controls) within the European Prospective Investigation into Cancer and Nutrition. Se was measured by total reflection X-ray fluorescence and SePP by… CONTINUE READING
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