Selenium nanoparticles as a carrier of 5-fluorouracil to achieve anticancer synergism.

@article{Liu2012SeleniumNA,
  title={Selenium nanoparticles as a carrier of 5-fluorouracil to achieve anticancer synergism.},
  author={Wen Liu and Xiaoling Li and Y. B. Wong and Wenjie Zheng and Yibo Zhang and Wenqiang Cao and Tianfeng Chen},
  journal={ACS nano},
  year={2012},
  volume={6 8},
  pages={6578-91}
}
A simple method for preparing 5-fluorouracil surface-functionalized selenium nanoparticles (5FU-SeNPs) with enhanced anticancer activity has been demonstrated in the present study. Spherical SeNPs were capped with 5FU through formation of Se-O and Se-N bonds and physical adsorption, leading to the stable structure of the conjugates. 5FU surface decoration… CONTINUE READING