Selenium in human health and disease.

  title={Selenium in human health and disease.},
  author={Susan J Fairweather-Tait and Yongping Bao and Martin R Broadley and Rachel Collings and Dianne Ford and John E. Hesketh and Rachel K Hurst},
  journal={Antioxidants & redox signaling},
  volume={14 7},
This review covers current knowledge of selenium in the environment, dietary intakes, metabolism and status, functions in the body, thyroid hormone metabolism, antioxidant defense systems and oxidative metabolism, and the immune system. Selenium toxicity and links between deficiency and Keshan disease and Kashin-Beck disease are described. The relationships between selenium intake/status and various health outcomes, in particular gastrointestinal and prostate cancer, cardiovascular disease… CONTINUE READING
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