Selenium in biology: facts and medical perspectives.

  title={Selenium in biology: facts and medical perspectives.},
  author={J K{\"o}hrl and Regina Brigelius-Floh{\'e} and August Boeck and Roland G{\"a}rtner and Ortwin Meyer and Leopold Floh{\'e}},
  journal={Biological chemistry},
  volume={381 9-10},
Several decades after the discovery of selenium as an essential trace element in vertebrates approximately 20 eukaryotic and more than 15 prokaryotic selenoproteins containing the 21st proteinogenic amino acid, selenocysteine, have been identified, partially characterized or cloned from several species. Many of these proteins are involved in redox reactions with selenocysteine acting as an essential component of the catalytic cycle. Enzyme activities have been assigned to the glutathione… CONTINUE READING
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