Selenium deficiency abrogates inflammation-dependent plasma cell tumors in mice.

@article{Felix2004SeleniumDA,
  title={Selenium deficiency abrogates inflammation-dependent plasma cell tumors in mice.},
  author={Klaus Felix and Simone Gerstmeier and Antonios Kyriakopoulos and Ola Mae Zack Howard and Hui-fang Dong and Michael W Eckhaus and Dietrich Behne and Georg W. Bornkamm and Siegfried Janz},
  journal={Cancer research},
  year={2004},
  volume={64 8},
  pages={2910-7}
}
The role of the micronutrient, selenium, in human cancers associated with chronic inflammations and persistent infections is poorly understood. Peritoneal plasmacytomas (PCTs) in strain BALB/c (C), the premier experimental model of inflammation-dependent plasma cell transformation in mice, may afford an opportunity to gain additional insights into the significance of selenium in neoplastic development. Here, we report that selenium-depleted C mice (n = 32) maintained on a torula-based low… CONTINUE READING