Selenium biochemistry and its role for human health.

  title={Selenium biochemistry and its role for human health.},
  author={Marco Antonio Leon Roman and Petru Jitaru and Carlo Barbante},
  journal={Metallomics : integrated biometal science},
  volume={6 1},
Despite its very low level in humans, selenium plays an important and unique role among the (semi)metal trace essential elements because it is the only one for which incorporation into proteins is genetically encoded, as the constitutive part of the 21st amino acid, selenocysteine. Twenty-five selenoproteins have been identified so far in the human proteome. The biological functions of some of them are still unknown, whereas for others there is evidence for a role in antioxidant defence, redox… CONTINUE READING
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