Selegiline’s neuroprotective capacity revisited

@article{Riederer2003SelegilinesNC,
  title={Selegiline’s neuroprotective capacity revisited},
  author={Peter Franz Riederer and Lenard Lachenmayer},
  journal={Journal of Neural Transmission},
  year={2003},
  volume={110},
  pages={1273-1278}
}
MAO-inhibitors in Parkinson's Disease
TLDR
In general, the clinical use of MAO-I nowadays is underestimated and there should be more efforts to evaluate their clinical potency as antidepressants and antidementive drugs in addition to the final proof of their disease-modifying potential.
Molecular mechanism of the relation of monoamine oxidase B and its inhibitors to Parkinson's disease: possible implications of glial cells.
Monoamine oxidases A and B (MAO A and MAO B) are the major enzymes that catalyze the oxidative deamination of monoamine neurotaransmitters such as dopamine (DA), noradrenaline, and serotonin in the
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TLDR
The role of MAOB is redefined for the aberrant suppression and deterioration of dopaminergic neurons through excessive GABA and H2O2 synthesis of reactive astrocytes in PD.
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TLDR
An evidence‐based review of Parkinson’s disease treatments and guidance to improve clinical management and outcomes in older people is presented.
Safety and Tolerability of Pharmacotherapies for Parkinson’s Disease in Geriatric Patients
TLDR
Geriatric patients with Parkinson’s disease experience a specific profile of comorbidities and an international register concerning issues of safer drug application and monitoring could help to implement a better treatment.
Practical synthesis of silyl-protected and functionalized propargylamines using nanostructured Ag/TiO2 and Pt/TiO2 as active recyclable catalysts
Herein we report the use of Ag/TiO2 and Pt/TiO2 nanocatalysts to promote the synthesis of a series of silyl-protected and functionalized propargylamine derivatives through alkyne–amine–aldehyde (A3)
90 years of monoamine oxidase: some progress and some confusion
  • K. Tipton
  • Biology
    Journal of Neural Transmission
  • 2018
TLDR
This account concentrates key advances that explain why the monoamine oxidases remain of pharmacological and biochemical interest and on some areas of continuing uncertainty.
Biocatalysis for synthesis of pharmaceuticals.
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