Selectivity of the ubiquitin-binding modules.

  title={Selectivity of the ubiquitin-binding modules.},
  author={Simin Rahighi and Ivan Dikic},
  journal={FEBS letters},
  volume={586 17},
Ubiquitin-binding modules are constituents of cellular proteins that mediate the effects of ubiquitylation by making transient, non-covalent interactions with ubiquitin molecules. While some ubiquitin-binding modules bind single ubiquitin moieties, others are selective for specific ubiquitin chains of different linkage types and lengths. In recent years, functions of ubiquitin chains that are polymerized through their Lys or N-terminal Met (i.e. linear chains) residues have been linked to a… CONTINUE READING

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