Selectivity in Physiological Action of Nitric Oxide: A Hypothetical Mechanism

@article{Titov2017SelectivityIP,
  title={Selectivity in Physiological Action of Nitric Oxide: A Hypothetical Mechanism},
  author={Vasiliy Titov and Antonina Dolgorukova and Viacheslav A. Petrov and Andreyan N. Osipov},
  journal={Bulletin of Experimental Biology and Medicine},
  year={2017},
  volume={163},
  pages={726-730}
}
The study showed that dinitrosyl iron complex (NO)2Fe(RS)2 containing the thiolate ligands, which is the basic physiological donor of NO, can transfer NO to other molecule only at the moment of rearrangement. This rearrangement can occur during interaction of the complex with more effective iron chelators than the thiolate ligands. In the absence of NO trap… CONTINUE READING