Selectively bred rodents as models of depression and anxiety.

@article{Wegener2011SelectivelyBR,
  title={Selectively bred rodents as models of depression and anxiety.},
  author={Gregers Wegener and Aleksander A. Math{\'e} and Inga D. Neumann},
  journal={Current topics in behavioral neurosciences},
  year={2011},
  volume={12},
  pages={
          139-87
        }
}
Stress related diseases such as depression and anxiety have a high degree of co morbidity, and represent one of the greatest therapeutic challenges for the twenty-first century. The present chapter will summarize existing rodent models for research in psychiatry, mimicking depression- and anxiety-related diseases. In particular we will highlight the use of selective breeding of rodents for extremes in stress-related behavior. We will summarize major behavioral, neuroendocrine and neuronal… CONTINUE READING
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