Selective vulnerability of brain regions to oxidative stress in a non-coma model of insulin-induced hypoglycemia.

@article{Haces2010SelectiveVO,
  title={Selective vulnerability of brain regions to oxidative stress in a non-coma model of insulin-induced hypoglycemia.},
  author={Mar{\'i}a L Haces and T. M{\'e}ndez Montiel and Lourdes Massieu},
  journal={Neuroscience},
  year={2010},
  volume={165 1},
  pages={28-38}
}
Insulin-induced hypoglycemia causes the death of neurons in particular brain regions including the cerebral cortex, the striatum and the hippocampus, while the cerebellum and the brain stem are more resistant. The mechanisms underlying this selective vulnerability to hypoglycemic damage are unknown. In the present study we have analyzed the presence of lipoperoxidation products and nitrosilated protein residues in different rat brain regions during and after the induction of hypoglycemia… CONTINUE READING
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