Selective vagal denervation of the atria eliminates heart rate variability and baroreflex sensitivity while preserving ventricular innervation.

@article{Chiou1998SelectiveVD,
  title={Selective vagal denervation of the atria eliminates heart rate variability and baroreflex sensitivity while preserving ventricular innervation.},
  author={C W Chiou and Douglas Peter Zipes},
  journal={Circulation},
  year={1998},
  volume={98 4},
  pages={360-8}
}
BACKGROUND The purpose of this study was to test whether radiofrequency catheter ablation (RFCA) of 3 epicardial fat pads that resulted in efferent vagal denervation of the atria and sinus and atrioventricular nodes also denervated the ventricles. METHODS AND RESULTS Vagal innervation of the ventricles was determined by measuring prolongation of ventricular effective refractory period induced by bilateral vagal stimulation (20 Hz, 10 V, 4 ms). Changes in heart rate variability (HRV) and… CONTINUE READING
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Heart rate variability : standards of measurement , physiological interpretation , and clinical use

  • A Malliani, M Pagani, F Lombardi, S Cerutti
  • Circulation
  • 1996

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