Selective vagal afferent dysfunction in dogs with congenital idiopathic megaoesophagus.

@article{Holland2002SelectiveVA,
  title={Selective vagal afferent dysfunction in dogs with congenital idiopathic megaoesophagus.},
  author={Christopher T. Holland and Paul M. Satchell and Brian R. H. Farrow},
  journal={Autonomic neuroscience : basic & clinical},
  year={2002},
  volume={99 1},
  pages={18-23}
}
Congenital idiopathic megaoesophagus (CIM) is a rare, naturally occurring disorder of the dog that is characterised by deficient motility and dilatation of the oesophagus. Recent studies indicate that the vagal sensory system mediating reflexes induced by oesophageal distension is defective in, and may underlie the pathomechanism of this disorder. We sought to establish whether other distension sensitive vagal afferent systems were impaired in CIM, or whether the vagal afferent dysfunction was… CONTINUE READING

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