Selective up-regulation of the soluble pattern-recognition receptor pentraxin 3 and of vascular endothelial growth factor in giant cell arteritis: relevance for recent optic nerve ischemia.

@article{Baldini2012SelectiveUO,
  title={Selective up-regulation of the soluble pattern-recognition receptor pentraxin 3 and of vascular endothelial growth factor in giant cell arteritis: relevance for recent optic nerve ischemia.},
  author={Mattia Baldini and Norma Maugeri and Giuseppe A Ramirez and Chiara Giacomassi and Alessandra Castiglioni and Sergio Prieto-Gonz{\'a}lez and Marc Corbera-Bellalta and Gabriele di Comite and Ilenia Papa and Giacomo Dell'antonio and Enrico Ammirati and Ivan Cuccovillo and Viviana Vecchio and Alberto Mantovani and Patrizia Rovere-Querini and Maria Grazia Sabbadini and Maria C Cid and Angelo A. Manfredi},
  journal={Arthritis and rheumatism},
  year={2012},
  volume={64 3},
  pages={854-65}
}
OBJECTIVE To assess local expression and plasma levels of pentraxin 3 (PTX3) in patients with giant cell arteritis (GCA). METHODS Plasma and serum samples were obtained from 75 patients with GCA (20 of whom had experienced optic nerve ischemia in the previous 3 weeks and 24 of whom had experienced symptom onset in the previous 6 months and had no history of optic nerve ischemia) and 63 controls (35 age-matched healthy subjects, 15 patients with rheumatoid arthritis, and 13 patients with… CONTINUE READING
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Deficiency of the long pentraxin PTX3 promotes vascular inflammation and atherosclerosis

  • GD Norata, P Marchesi, VK Pulakazhi Venu, F Pasqualini, A Anselmo, F Moalli
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