Selective translation of mRNA controls the pattern of protein synthesis during early development of the surf clam, Spisula solidissima

@article{Rosenthal1980SelectiveTO,
  title={Selective translation of mRNA controls the pattern of protein synthesis during early development of the surf clam, Spisula solidissima},
  author={Eric T. Rosenthal and Tim Hunt and Joan V. Ruderman},
  journal={Cell},
  year={1980},
  volume={20},
  pages={487-494}
}
TRANSLATIONAL REGULATION OF GENE EXPRESSION IN EARLY DEVELOPMENT
TLDR
This result strongly suggests that the inactivity of maternal mRNAs in the oocyte is not due to their being stored as translationally incompetent larger precursor forms, and there is a good correlation between possession of a poly(A) tail and translational activity in vivo.
Cytoplasmic regulation of translation during Ilyanassa embryogenesis
TLDR
It was shown that actin present in the unfertilized egg and are therefore are inactive during early cleavage, and are translated lobeless, actinomycin D-treated blastulae and in that have been aged for 24h, suggesting the activation of controlled by cytoplasmic factors that function cleavage and nuclear activity.
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References

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Regulation of maternal mRNA translation in developing embryos of the surf clam Spisula solidissima
TLDR
It is reported here that part of the non-polysomal mRNA of embryos consists of maternal mRNA species which are inefficiently translated after fertilisation, which suggests that part is synthesised soon after fertilising and already translated at the early cleavage stage.
An efficient mRNA-dependent translation system from reticulocyte lysates.
TLDR
A simple method is described for converting a standard rabbit reticulocyte cell-free extract (lysate) into an mRNA-dependent protein synthesis system, and no residual nuclease activity could be detected, and the tRNA is functionally unimpaired.
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